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J. Venom. Anim. Toxins incl. Trop. Dis. V.20, 2014. Case report - ISSN 1678-9199. |
Lepromatous leprosy and perianal tuberculosis: a case report and literature review
1Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP – Univ Estadual Paulista), Botucatu São Paulo State, Brasil
2Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP – Univ Estadual Paulista), Botucatu, São Paulo State, Brazil
3Departamento de Dermatologia e Radioterapia, Faculdade de Medicina de Botucatu, UNESP, Distrito de Rubião Junior, Botucatu, SP CEP 18618-970, Brasil
ABSTRACT
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it may spread to other organs and cause an extrapulmonary infection. Both mycobacterial infections are endemic in developing countries including Brazil, and cases of coinfection have been reported in the last decade. Nevertheless, simultaneous occurrence of perianal cutaneous tuberculosis and erythema nodosum leprosum is very rare, even in countries where both mycobacterial infections are endemic.
Key words: Mycobacteria; Leprosy; Tuberculosis; Erythema nodosum leprosum
Received: March 31, 2014; Accepted: August 19, 2014