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J. Venom. Anim. Toxins incl. Trop. Dis.

V.20, 2014.

Case report - ISSN 1678-9199.

 

Lepromatous leprosy and perianal tuberculosis: a case report and literature review

 
Maria Rita Parise-Fortes1 3, Joel Carlos Lastória1, Silvio Alencar Marques1, Maria Stella Ayres Putinatti1, Hamilton Ometto Stolf1, Mariângela Ester Alencar Marques2, Vidal Haddad1

 

1Department of Dermatology, Botucatu Medical School, São Paulo State University (UNESP – Univ Estadual Paulista), Botucatu São Paulo State, Brasil

2Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP – Univ Estadual Paulista), Botucatu, São Paulo State, Brazil

3Departamento de Dermatologia e Radioterapia, Faculdade de Medicina de Botucatu, UNESP, Distrito de Rubião Junior, Botucatu, SP CEP 18618-970, Brasil

 

ABSTRACT

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it may spread to other organs and cause an extrapulmonary infection. Both mycobacterial infections are endemic in developing countries including Brazil, and cases of coinfection have been reported in the last decade. Nevertheless, simultaneous occurrence of perianal cutaneous tuberculosis and erythema nodosum leprosum is very rare, even in countries where both mycobacterial infections are endemic.

 

Key words: Mycobacteria; Leprosy; Tuberculosis; Erythema nodosum leprosum

 

 

Received: March 31, 2014; Accepted: August 19, 2014

 

Corresponding author: Maria R Parise-Fortes mfortes@fmb.unesp.br

 

Ethics committee approval

The case report was submitted for analysis and approved by the Research Ethics Committee of the Botucatu Medical School (CEP), in accordance with resolution 466/2012.

 

Consent

Written informed consent was obtained from the patient for publication of this case report and the figures.

 

Competing interests

The authors declare that they have no competing interests.

 

Authors’ contributions

All authors contributed to the design of the study and manuscript preparation. All authors have read and approved the final manuscript.