Mycobacterium genavense infection in two species of captive snakes
Leila Sabrina Ullmann1 , Ramiro das Neves Dias-Neto2 , Didier Quevedo Cagnini3 , Ricardo Seiti Yamatogi1 , Jose Paes Oliveira-Filho3 , Viviane Nemer4 , Rodrigo Hidalgo Friciello Teixeira2 , Alexander Welker Biondo5 and João Pessoa Araújo Jr.1* [ + show more ]
Received: 3 February 2016 | Accepted: 10 September 2016 | Published: 18 October 2016
https://doi.org/10.1186/s40409-016-0082-7
Abstract
Background: Mycobacterium is an important zoonotic agent with companion, livestock and wildlife animals reportedly playing a role as reservoirs. Although its association with reptiles has been described, the disease cycle remains to be fully established, particularly in snakes. Accordingly, this study aimed to report the occurrence of mycobacteriosis with clinical pneumonia in one exotic python snake (Python molurus) and one native green snake (Philodryas olfersii) from the Sorocaba Zoo, São Paulo state, Brazil. Methods: Diagnosis was based on necropsy, histopathological examination, Ziehl-Neelsen stain and immunohistochemistry. Results: Using a nested PCR followed by DNA sequencing and bioinformatics analysis, the causative Mycobacterium species was identified as Mycobacterium genavense. Conclusion: Mycobacterium genavense is an infectious zoonotic agent of animal and public health concerns.
Keywords: Captive snakes, Mycobacterium, Public health